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Updated: Jun 28, 2025

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
Published on: October 13, 2023
Medical knowledge graph completion via fusion of entity description and type information
Xiaochen Wang1, Runtong Zhang1, Butian Zhao1
1Department of Information Management, Beijing Jiaotong University, Beijing, 100044, China.
Abstract:
Medical Knowledge Graphs (MKGs) are vital in propelling big data technologies in healthcare and facilitating the realization of medical intelligence. However, large-scale MKGs often exhibit characteristics of data sparsity and missing facts. Following the latest advances, knowledge embedding addresses these problems by performing knowledge graph completion. Most knowledge embedding algorithms rely solely on triplet structural information, overlooking the rich information hidden within entity property sets, leading to bottlenecks in performance enhancement when dealing with the intricate relations of MKGs. Inspired by the semantic sensitivity and explicit type constraints unique to the medical domain, we propose BioBERT-based graph embedding model. This model represents an evolvable framework that integrates graph embedding, language embedding, and type information, thereby optimizing the utility of MKGs. Our study utilizes not only WordNet as a benchmark dataset but also incorporates MedicalKG to compare and corroborate the specificity of medical knowledge. Experimental results on these datasets indicate that the proposed fusion framework achieves state-of-art (SOTA) performance compared to other baselines. We believe that this incremental improvement provides promising insights for future medical knowledge graph completion endeavors.
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