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Related Experiment Video

Updated: Jun 28, 2025

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
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Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

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Engineering complex tissue-like microenvironments with biomaterials and biofabrication.

Gregor Miklosic1, Stephen J Ferguson2, Matteo D'Este3

  • 1AO Research Institute Davos, Davos, Switzerland; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Trends in Biotechnology
|April 24, 2024
PubMed
Summary
This summary is machine-generated.

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Reduced paraspinal muscle endurance and electromyographic fatigability are associated with greater global spinal imbalance in symptomatic lumbar spinal stenosis.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026
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Translation-driven design: development of an antibiotic-loaded hydrogel for the management of orthopaedic device-related infection.

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Critical velocity metric derived from dynamic finite element analysis classifies hip fracture risk in a clinical cohort.

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Ex vivo mechanical evaluation of anatomically and mechanically conforming patient-specific lumbar spinal fusion cages designed by full-scale topology optimization.

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3D Printing of Dense and Anisotropic Collagen/Hyaluronan Hydrogels for Biofabrication of Layered Annulus Fibrosus Tissue.

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JBMR plus·2026

Tissue engineering advances require mimicking complex tissue structures and microenvironments. Innovative biofabrication and biomaterials are key to creating high-fidelity models for better therapies and understanding tissue function.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Tissue engineering aims to replicate functional and structural complexity for system modeling and organ regeneration.
  • Microenvironmental factors like anisotropy, heterogeneity, and spatiotemporal cues are critical for tissue development and function.

Purpose of the Study:

  • To review key structural and compositional aspects of tissues.
  • To outline current biofabrication strategies for mimicking tissue complexity.
  • To identify challenges and future research directions in high-fidelity tissue engineering.

Main Methods:

  • Literature review of tissue engineering advancements.
  • Analysis of biofabrication strategies and biomaterial design.
  • Exploration of methods to recapitulate microenvironmental cues.
Keywords:
3D modelsanisotropybiofabricationheterogeneitytissue engineeringvasculature

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Related Experiment Videos

Last Updated: Jun 28, 2025

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

15.8K
Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

9.4K
Sandwich-like Microenvironments to Harness Cell/Material Interactions
06:50

Sandwich-like Microenvironments to Harness Cell/Material Interactions

Published on: August 4, 2015

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Main Results:

  • Novel biofabrication strategies and biomaterial designs enable the creation of high-fidelity biomimetic structures.
  • These advancements offer opportunities for deeper understanding of tissue function.
  • Progress is being made in reproducing complex microenvironmental features.

Conclusions:

  • Mimicking tissue complexity is essential for advancing tissue engineering.
  • Innovative fabrication and materials are crucial for developing superior therapies.
  • Further research is needed to overcome current challenges and explore future avenues.