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Related Concept Videos

Pneumothorax-II01:27

Pneumothorax-II

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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

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Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
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Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

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Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Chronic Obstructive Pulmonary Disease-V: Nursing Management01:30

Chronic Obstructive Pulmonary Disease-V: Nursing Management

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Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment
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Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

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Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
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Related Experiment Video

Updated: Jun 28, 2025

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
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Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

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Factors Associated With Margin Positivity After Lung Resection Surgery.

Hamza Rshaidat1, Gregory L Whitehorn2, Micaela Collins1

  • 1Department of Surgery, Division of Esophageal and Thoracic Surgery, Thomas Jefferson University Hospital, Philadelphia, PA.

Clinical Lung Cancer
|April 24, 2024
PubMed
Summary

Open lung cancer surgery is linked to higher positive margins compared to robotic or VATS approaches. Factors like larger tumors and advanced stage also increase positive margin risk, impacting patient outcomes.

Keywords:
Complete resectionLung cancerNon–small-cell lung cancerRobotic surgerySurgical margin

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Area of Science:

  • Thoracic Surgery
  • Surgical Oncology
  • Pulmonology

Background:

  • Surgical resection is a primary treatment for non-small-cell lung cancer.
  • Minimally invasive techniques like robotic and video-assisted thoracoscopic surgery (VATS) have gained prominence.
  • Understanding factors influencing margin positivity is crucial for optimizing surgical outcomes.

Purpose of the Study:

  • To investigate factors associated with positive surgical margins in lung cancer resection.
  • To compare margin positivity rates across different surgical approaches: robotic, VATS, and open surgery.

Main Methods:

  • Retrospective cohort study using the National Cancer Database (2010-2019).
  • Inclusion of patients aged 18+ undergoing surgical lung resection for non-small-cell lung cancer.
  • Analysis of demographic, clinical, and outcome variables (30/90-day mortality, readmission) using logistic regression.

Main Results:

  • 4.2% of 226,884 patients had positive margins.
  • Positive margins correlated with increased 30-day and 90-day mortality and readmission rates.
  • Factors associated with positive margins included older age, male sex, open resection, wedge resection, higher clinical stage, larger tumor size, squamous/adenosquamous histology, and higher comorbidity index.

Conclusions:

  • No significant difference in margin positivity between robotic and VATS resections.
  • Open resection was associated with higher rates of positive margins.
  • Tumor size, clinical stage, histology (squamous/adenosquamous), male sex, and wedge resection independently increased positive margin risk.