Occupational patterns of opioid-related harms comparing a cohort of formerly injured workers to the general population in Ontario, Canada
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Work-related injuries significantly increase the risk of opioid-related harms, including poisonings and mental health disorders, compared to the general population. Prevention strategies for occupational injuries and work disability are crucial.
Area Of Science
- Occupational Health
- Public Health
- Epidemiology
Background
- A hypothesis suggests work-related injuries are a risk factor for opioid-related harms, but empirical data are limited.
- Understanding this relationship is crucial for public health interventions and worker safety.
Purpose Of The Study
- To compare the incidence of opioid-related harms in formerly injured workers versus the general population in Ontario, Canada.
- To identify specific occupations and industries with elevated risks of opioid-related harms.
Main Methods
- A cohort study linked workers' compensation claimants (1983-2019) to emergency department and hospitalization records (2006-2020).
- Incident rates of opioid-related poisonings and mental/behavioral disorders were calculated and compared using standardized incidence ratios (SIRs).
- Analyses adjusted for age, sex, year, and region.
Main Results
- Formerly injured workers showed significantly elevated rates of opioid-related poisonings in emergency departments (SIR=2.41) and hospitalizations (SIR=1.54).
- Elevated risks were also observed for opioid-related mental and behavioral disorders (ED: SIR=1.86; hospitalizations: SIR=1.42).
- Construction, materials handling, processing, and machining occupations had higher risks, while teaching occupations had lower risks.
Conclusions
- The study supports the hypothesis that work-related injuries are a preventable risk factor for opioid-related harms.
- Primary prevention of occupational injuries and secondary prevention of work disability are recommended.
- Interventions targeting long-term opioid use in injured workers are warranted.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):
When one is faced with too much information
When the time to make a decision is limited
When the decision to be made is unimportant
When there is access to very...