Related Experiment Video
Updated: May 7, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Horizontal GBR with anorganic equine bone combined with a customized titanium mesh
Francesco Orlando1,2, Simone Foiani1, Claudia Dellavia3
1Private Practice, Centro Odontoiatrico e Protesico Civitali S.R.L. Milan Italy.
This case report details fixed rehabilitation of the lower left arch using a customized titanium mesh and a novel equine bone substitute after horizontal guided bone regeneration (GBR). The study highlights a successful approach for complex dental implant restoration.
Area of Science:
- Oral surgery
- Periodontology
- Biomaterials science
Background:
- Guided bone regeneration (GBR) is a key technique in dental implantology to augment bone volume.
- Horizontal bone defects present unique challenges for GBR and subsequent prosthetic rehabilitation.
- The development of advanced bone substitutes is crucial for predictable GBR outcomes.
Observation:
- A patient with a horizontal defect in the lower left arch underwent GBR.
- A customized titanium mesh was employed to contain the bone graft.
- A novel slow-resorption bone substitute of equine origin was utilized.
Findings:
- The combination of a customized titanium mesh and the equine bone substitute facilitated successful bone regeneration.
- Fixed prosthetic rehabilitation of the lower left arch was achieved.
- The slow resorption rate of the equine bone substitute may contribute to long-term stability.
Implications:
- This case report suggests a viable treatment protocol for horizontal bone augmentation in the mandible.
- Customized titanium mesh offers a reliable solution for defect containment in GBR.
- Equine-derived bone substitutes show promise as effective biomaterials in regenerative dentistry.
More Related Videos
09:35Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
06:05Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
Published on: July 14, 2023
Related Concept Videos
Bone Structure
The Bone Matrix
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...