Changes in Testing and Treatment Methods in Osteoporosis Care
Takashi Nagai1,2, Koji Ishikawa2, Koki Tsuchiya2
1Department of Rehabilitation Medicine, Showa University School of Medicine, Tokyo, Japan.
Journal of Osteoporosis
|April 25, 2024
Summary
Physicians increasingly use bone density scans and blood tests for osteoporosis diagnosis. Treatment trends shifted towards medications that rapidly increase bone mineral density, improving fracture prevention in bedridden patients.
Area of Science:
- Orthopedics
- Endocrinology
- Geriatrics
Background:
- Osteoporosis treatment is vital for fracture prevention, especially in vulnerable bedridden populations.
- Understanding physician diagnostic and treatment trends is key to optimizing patient care.
Purpose of the Study:
- To investigate the 5-year trend in osteoporosis diagnostic and treatment preferences among physicians.
- To assess changes in the utilization of bone mineral density measurements and bone metabolic markers.
- To identify shifts in the prescription patterns of osteoporosis pharmacotherapies.
Main Methods:
- A comparative questionnaire survey of hypothetical clinical cases administered in 2015 and 2020.
- Targeting physicians in local clinics and hospitals, with a focus on orthopaedic surgeons (n=74).
- Analysis of responses regarding diagnostic tests and therapeutic agent choices.
Main Results:
- Significant increase in physician preference for bone mineral density measurements (lumbar spine and hip).
- Marked rise in the use of bone metabolic markers (NTX, P1NP, TRACP-5b) due to convenience and reliability.
- Shift in pharmacotherapy from bisphosphonates towards parathyroid hormone and romosozumab for rapid bone density enhancement.
Conclusions:
- Physician adoption of bone density testing and metabolic markers for osteoporosis diagnosis has grown.
- There is a clear trend towards early use of potent anabolic agents to rapidly improve bone mineral density.
- These shifts indicate an evolving approach to osteoporosis management, aiming for earlier and more effective fracture risk reduction.
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