Paradoxical herniation associated with hyperbaric oxygen therapy after decompressive craniectomy: A case report
Zhong-Xing Ye1, Xin-Xin Fu1, Yang-Zong Wu2
1Department of Neurosurgery, The Second People's Hospital of Fujian Province (The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine), Fuzhou 350001, Fujian Province, China.
Background:
Whether hyperbaric oxygen therapy (HBOT) can cause paradoxical herniation is still unclear.
Case Summary:
A 65-year-old patient who was comatose due to brain trauma underwent decompressive craniotomy and gradually regained consciousness after surgery. HBOT was administered 22 d after surgery due to speech impairment. Paradoxical herniation appeared on the second day after treatment, and the patient's condition worsened after receiving mannitol treatment at the rehabilitation hospital. After timely skull repair, the paradoxical herniation was resolved, and the patient regained consciousness and had a good recovery as observed at the follow-up visit.
Conclusion:
Paradoxical herniation is rare and may be caused by HBOT. However, the underlying mechanism is unknown, and the understanding of this phenomenon is insufficient. The use of mannitol may worsen this condition. Timely skull repair can treat paradoxical herniation and prevent serious complications.
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