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Rare COVID-19 vaccine side effects got lost in the shuffle. Primary cutaneous lymphomas following COVID-19 vaccination: a systematic review

  • 0Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.
Frontiers in Medicine +

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April 25, 2024

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April 25, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

COVID-19 vaccination may be associated with cutaneous lymphomas (CLs), particularly indolent T-cell types. While a definitive causal link is unclear, monitoring patients with lymphoproliferative disorders post-vaccination is recommended.

Area Of Science

  • Dermatology
  • Oncology
  • Immunology

Background

  • COVID-19 vaccines are safe and effective but can cause cutaneous side effects.
  • Concerns exist regarding a potential association between COVID-19 vaccination and primary cutaneous lymphomas (CLs).

Conclusions

  • An association between CLs and immune stimulation from COVID-19 vaccination is suggested.
  • Post-vaccine CLs may involve cytokine interplay and disrupted signaling pathways.
  • Establishing causality is challenging due to low incidence, but monitoring is advised for at-risk patients.

Keywords: