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Mind the Gap in Kidney Care: Translating What We Know Into What We Do
Valerie A Luyckx1, Katherine R Tuttle2, Dina Abdellatif3
1Department of Public and Global Health, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Abstract:
Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. The time is now to narrow the gap between what we know and what we do. Clear guidelines exist for the prevention and management of common risk factors for kidney disease, such as hypertension and diabetes, but only a fraction of people with these conditions worldwide are diagnosed, and even fewer are treated to target. Similarly, the vast majority of people living with kidney disease are unaware of their condition, because in the early stages it is often silent. Even among patients who have been diagnosed, many do not receive appropriate treatment for kidney disease. Considering the serious consequences of kidney disease progression, kidney failure, or death, it is imperative that treatments are initiated early and appropriately. Opportunities to diagnose and treat kidney disease early must be maximized beginning at the primary care level. Many systematic barriers exist, ranging from patient to clinician to health systems to societal factors. To preserve and improve kidney health for everyone everywhere, each of these barriers must be acknowledged so that sustainable solutions are developed and implemented without further delay. DOI: 10.52547/ijkd.8216.
Insights
Bridging the gap between kidney disease knowledge and practice is crucial. Early diagnosis and treatment, despite existing guidelines, are hindered by numerous barriers, necessitating immediate action.
Area of Science:
- Nephrology
- Public Health
- Translational Medicine
Background:
- Delay in translating kidney disease treatments from evidence to practice is significant.
- Effective interventions exist to prevent or slow kidney disease, yet their implementation lags.
- Many individuals with risk factors like hypertension and diabetes remain undiagnosed or undertreated.
Purpose of the Study:
- To highlight the critical delay in implementing evidence-based kidney disease treatments.
- To emphasize the need to accelerate the adoption of preventive and therapeutic strategies.
- To call for the maximization of early diagnosis and treatment opportunities at the primary care level.
Main Methods:
- Review of current guidelines for kidney disease risk factor management.
- Analysis of barriers to diagnosis and treatment across patient, clinician, and health system levels.
- Discussion of the silent nature of early-stage kidney disease and its impact on awareness.
Main Results:
- A substantial gap exists between kidney disease knowledge and clinical practice.
- A small fraction of individuals with hypertension and diabetes receive adequate diagnosis and treatment.
- The majority of kidney disease patients are unaware of their condition, and many diagnosed patients lack appropriate care.
Conclusions:
- Urgent action is required to narrow the gap between kidney disease knowledge and practice.
- Systematic barriers impede early diagnosis and treatment, necessitating comprehensive solutions.
- Addressing these barriers is essential for preserving and improving global kidney health.
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