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Presumed fluoxetine maculopathy
N Moreno Benito1, P B Blasco Palacio1, I Rodríguez García1
1Servicio Oftalmología, Hospital de Basurto, Bilbao, Spain.
Archivos De La Sociedad Espanola De Oftalmologia
|April 25, 2024
Summary
Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), may cause bilateral maculopathy. Ocular symptoms and optical coherence tomography (OCT) findings in this case align with previously reported SSRI maculopathy.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressants.
- Previous reports have linked SSRI-induced maculopathy primarily to sertraline.
- The biological mechanisms of SSRIs suggest potential for similar ocular side effects across different agents.
Observation:
- A unique case of simultaneous bilateral maculopathy is presented.
- The patient's maculopathy was presumed to be linked to fluoxetine intake.
- Optical coherence tomography (OCT) revealed subfoveal outer retinal layer disruption in both eyes.
Findings:
- Fluoxetine, despite not being previously implicated, demonstrated a similar maculopathy profile.
- The observed OCT findings and ocular symptoms mirrored those of sertraline-induced maculopathy.
- This case highlights fluoxetine as a potential cause of SSRI maculopathy.
Implications:
- Ophthalmologists and clinicians should consider fluoxetine as a potential cause of maculopathy.
- Increased awareness of ocular side effects associated with fluoxetine is warranted.
- Further investigation into fluoxetine's ocular toxicity may be necessary.
Keywords:
Capas externas de la retinaDisrupciónDisruptionFluoxetinaFluoxetineISRSMaculopathyMaculopatíaOCTOuter retinal layerSSRIsMore Related Videos
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