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Cardiovascular Risk Profiling Using the Globorisk Calculator among Noncommunicable Disease Patients Attending Primary
Sitanshu S Kar1, Sivaranjini Kannusamy1, Tanveer Rehman2
1Department of Preventive and Social Medicine, PGIMER, Chandigarh, India.
Insights
The Globorisk chart identifies more patients at high risk for cardiovascular disease (CVD) events than the WHO/ISH chart. There was no agreement between the two CVD risk prediction tools.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Cardiovascular diseases (CVDs) are a leading cause of death in developing nations.
- Noncommunicable diseases (NCDs) pose a significant public health challenge globally.
Purpose of the Study:
- To stratify NCD patients' 10-year CVD risk using the Globorisk chart.
- To compare Globorisk chart risk stratification with the WHO/ISH risk strata.
- To assess agreement between country-specific and international CVD risk prediction tools.
Main Methods:
- A cross-sectional study was conducted in 2018 in Puducherry, India.
- Adults attending NCD clinics were included (n=760).
- Globorisk and WHO/ISH risk calculators were used to determine 10-year CVD risk.
Main Results:
- Globorisk identified 22.1% of participants with <10% 10-year CVD risk, versus 71.1% by WHO/ISH.
- No agreement was found between the Globorisk and WHO/ISH risk charts (k=0.0174, P=0.26).
- Globorisk classified a higher proportion of patients into higher CVD risk categories.
Conclusions:
- The Globorisk chart identifies more patients at higher risk for CVD events compared to WHO/ISH charts.
- Discrepancies highlight the need for careful selection of CVD risk assessment tools in different populations.
- Further research is needed to validate CVD risk prediction models in diverse settings.
Background:
Cardiovascular diseases (CVDs) account for over three-quarters of all deaths taking place in developing nations.
Objective:
The present study aims to stratify noncommunicable disease (NCD) patients using the Globorisk chart for predicting their 10-year risk of a major (fatal or nonfatal) CVD event and to estimate the level of agreement between this country-specific chart and the existing World Health Organization (WHO)/International Society of Hypertension (ISH) risk strata.
Methods:
A record-based cross-sectional analytical study was conducted in 2018 among adults attending the NCD clinic of one rural and one urban primary health center in Puducherry. Laboratory and office risk calculators of the Globorisk chart were used to calculate the risk.
Results:
The median age (interquartile range (IQR)) of the 760 study participants was 58 (50-65) years. When calculated using the Globorisk prediction chart, 22.1% (n = 168) of the participants had a <10% risk for any CVD event in the next 10 years, whereas the same risk was found in 71.1% (n = 540) by using the WHO/ISH risk chart. There was no agreement found between the two risk charts (k = 0.0174; P-value = 0.26).
Conclusion:
The Globorisk chart was found to identify more patients as belonging to the higher risk category as compared to WHO/ISH charts.
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