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Scanning reproducible brain-wide associations: sample size is all you need?

Xiang-Zhen Kong1,2, Chenghui Zhang1, Yinuo Liu1

  • 1Department of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou 310028, China.

Psychoradiology
|April 26, 2024
PubMed
Abstract

No abstract available in PubMed .

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...