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Updated: Jun 27, 2025

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Unusual Presentation of a Giant Cell Tumor of the Bone: A Case Report
Prachi Gedekar1, Atul Chavhan1, K M Hiwale1
1Pathology, Datta Meghe Institute of Medical Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Abstract:
Bone giant cell tumors (GCTs) are rare, non-cancerous tumors that mostly affect the meta-epiphyseal region of long bones in the legs and arms. We are reporting a case of GCT of bone of a 14-year-old male; it usually occurs in the age group of 20-40 years. The presence of multinucleated giant cells and stromal cells in the proximal diaphysis of the left tibia serves as a distinguishing characteristic. The majority of GCTs are benign; they have the potential to induce bone loss and can be locally aggressive. Treatment options often include surgery, and in some cases, medications like denosumab may be used to help shrink the tumor or manage recurrent cases.

