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Borderline Ventricles: From Evaluation to Treatment
Giuseppe Antonio Mazza1, Lilia Oreto2, Giulia Tuo3
1Division of Pediatric Cardiology, City of Health and Science University Hospital, 10126 Turin, Italy.
Insights
Pediatric cardiologists face challenges with borderline ventricles in congenital heart disease (CHD). This review aims to clarify when a ventricle is too small or large enough for surgical decisions.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Cardiac Surgery
Background:
- Borderline ventricles present diagnostic uncertainty in supporting systemic or pulmonary circulation.
- Congenital heart diseases (CHDs) frequently involve underdeveloped left or right ventricles.
- Current management lacks specific guidelines, leading to variable surgical approaches.
Purpose of the Study:
- To define criteria for assessing borderline ventricles in pediatric CHD.
- To aid clinicians in deciding between single-ventricle and biventricular surgical strategies.
- To improve long-term patient outcomes by optimizing surgical approach.
Main Methods:
- Literature review on ventricular size and function in CHD.
- Analysis of existing data on single-ventricle versus biventricular outcomes.
- Discussion of factors influencing surgical decision-making.
Main Results:
- Identification of key parameters for evaluating borderline ventricular adequacy.
- Highlighting the controversy and variability in current surgical management.
- Emphasizing the critical impact of this decision on lifelong patient health.
Conclusions:
- Establishing clearer guidelines for borderline ventricles is crucial.
- Standardizing surgical approaches can improve consistency and outcomes.
- Informed decision-making is vital for patients with CHD and borderline ventricles.
Abstract:
A heart with a borderline ventricle refers to a situation where there is uncertainty about whether the left or right underdeveloped ventricle can effectively support the systemic or pulmonary circulation with appropriate filling pressures and sufficient physiological reserve. Pediatric cardiologists often deal with congenital heart diseases (CHDs) associated with various degrees of hypoplasia of the left or right ventricles. To date, no specific guidelines exist, and surgical management may be extremely variable in different centers and sometimes even in the same center at different times. Thus, the choice between the single-ventricle or biventricular approach is always controversial. The aim of this review is to better define when "small is too small and large is large enough" in order to help clinicians make the decision that could potentially affect the patient's entire life.
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