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Do Concurrent Peri-Implantitis and Periodontitis Share Their Microbiotas? A Pilot Study.
Ana Parga1,2, José Manuel Pose-Rodríguez3, Andrea Muras1
1Department of Microbiology and Parasitology, CIBUS-Faculty of Biology, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Dentistry Journal
|April 26, 2024
Summary
Comparing oral lesions, this study found distinct microbial profiles in peri-implantitis versus periodontal disease. Peri-implantitis sites showed higher pathogen abundance, suggesting related yet different disease mechanisms.
Area of Science:
- Oral Microbiology
- Periodontology
- Implant Dentistry
Background:
- Contradictory literature exists on the etiological link between peri-implant and periodontal lesions.
- Understanding the microbial differences is crucial for diagnosing and treating these oral conditions.
Purpose of the Study:
- To compare the microbial compositions of concurrent peri-implant and periodontal lesions.
- To evaluate the impact of sample collection methods on microbial recovery.
- To elucidate the relationship between peri-implantitis and periodontal disease microbiomes.
Main Methods:
- Analysis of microbial samples from nine patients with concurrent lesions.
- Utilized Illumina MiSeq sequencing of 16S rRNA gene amplicons.
- Employed Principal Components Analysis for microbial community comparison.
- Compared microbial data based on collection methods (curettes vs. paper points) and lesion type.
Main Results:
- Paper points yielded a higher number of bacterial genera compared to curettes.
- Peri-implantitis samples exhibited greater bacterial diversity than matched periodontal samples.
- Periodontal samples contained more operational taxonomic units (OTUs) than peri-implantitis samples.
- Specific oral pathogens (e.g., Porphyromonas, Treponema) were more abundant in peri-implantitis.
- Aggregatibacter was more prevalent in periodontal lesions, indicating distinct microbial signatures.
Conclusions:
- Peri-implantitis and periodontal disease possess different yet related microbial profiles.
- Findings suggest distinct pathogenic mechanisms for peri-implant infections.
- Further research with larger sample sizes is warranted to confirm these microbial differences.
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