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Updated: Jun 27, 2025
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
Published on: October 16, 2018
High efficacy of CD19 CAR T cells in patients with transformed Waldenström macroglobulinemia
Eric Durot1, Damien Roos-Weil2, Adrien Chauchet3
1Department of Hematology, University Hospital of Reims, Reims, France.
Abstract:
Histologic transformation of Waldenström macroglobulinemia (HT-WM) carries a poor prognosis with standard treatments. Here, we report the first series of HT-WM treated with chimeric antigen receptor T cells showing a high efficacy and no unexpected toxicity.
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