Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

228
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
228

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultrasound-Informed State Estimation of Wrist Tremor Dynamics via Koopman Operator for Personalized Sensory Peripheral Nerve Stimulation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026
Same author

Cerebellar magnetization transfer ratio and its relationship to clinical outcomes in radiologically isolated syndrome and multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

A systematic review exploring the safety of deep brain stimulation at MRI field strengths beyond conventional field strengths: Opening the door to new imaging tools for neuromodulation.

AJNR. American journal of neuroradiology·2026
Same author

Exploring the Patient Pathway to Focused Ultrasound Ablation for Essential Tremor: A Mixed-Method Approach.

Stereotactic and functional neurosurgery·2026
Same author

Microstructural alterations of the human fornix in trigeminal neuralgia.

The journal of pain·2026
Same author

Transcranial ultrasound stimulation of motor networks in Parkinson's disease informed by local field potential dynamics.

Science translational medicine·2026
Same journal

FGF17 synergistically targets neuronal survival and oligodendrogenesis to restore stroke deficits.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same journal

Sotagliflozin improves cognitive deficits and attenuates neuroinflammation of Alzheimer's disease.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same journal

Neurological complications of current and emerging CAR-T cell therapies.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same journal

Hemodynamics Beyond Ischemic Zone Underlies Early Neurological Deterioration in Minor Stroke with Large Vessel Occlusion.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same journal

Nervonic acid and the long arc of therapeutic hope in X-linked adrenoleukodystrophy.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
Same journal

Long-term efficacy of subthalamic nucleus deep brain stimulation in focal motor seizures and implications for candidate selection.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026
See all related articles

Related Experiment Video

Updated: Jun 27, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.6K

Diffusion and functional MRI in surgical neuromodulation.

Nicole A Silva1, Jessica Barrios-Martinez2, Fang-Cheng Yeh2

  • 1Department of Neurological Surgery, University of North Carolina - Chapel Hill, Chapel Hill, NC, USA.

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics
|April 26, 2024
PubMed
Summary
This summary is machine-generated.

Advanced imaging techniques like diffusion MRI (dMRI) and functional MRI (fMRI) are enhancing surgical neuromodulation. This approach optimizes treatments for neurological disorders by viewing brain targets within networks, not just anatomy.

Keywords:
Deep brain nucleiDeep brain stimulationDiffusion MRIFunctional MRINeural circuitryNeuromodulation

More Related Videos

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.4K
Deep Brain Stimulation with Simultaneous fMRI in Rodents
11:09

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

14.1K

Related Experiment Videos

Last Updated: Jun 27, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.6K
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.4K
Deep Brain Stimulation with Simultaneous fMRI in Rodents
11:09

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

14.1K

Area of Science:

  • Neuroscience
  • Neurosurgery
  • Medical Imaging

Background:

  • Surgical neuromodulation, including deep brain stimulation (DBS) and focused ultrasound ablation (FUSA), has advanced significantly for neurological and psychiatric conditions.
  • Current neuromodulation often targets specific anatomical structures, but a network-based approach shows promise for optimizing outcomes.
  • Integrating advanced neuroimaging is crucial for refining these therapeutic strategies.

Purpose of the Study:

  • To provide a fundamental understanding of advanced neuroimaging techniques for clinicians and scientists involved in surgical neuromodulation.
  • To explore the synergistic potential of diffusion MRI (dMRI) and functional MRI (fMRI) in optimizing current and future neuromodulation therapies.
  • To highlight the need for focused research to enhance existing treatments and discover novel targets for neurological and psychiatric disorders.

Main Methods:

  • Review of current literature on surgical neuromodulation techniques (DBS, FUSA).
  • Integration of diffusion MRI (dMRI) and functional MRI (fMRI) principles within brain connectomics research.
  • Conceptualizing therapeutic targets as nodes within specific brain networks rather than isolated anatomical structures.

Main Results:

  • Advanced imaging, specifically dMRI and fMRI, facilitates a network-based approach to surgical neuromodulation targeting.
  • These techniques have improved targeting and programming in DBS and FUSA, expanding their application to diverse conditions.
  • The integration of dMRI and fMRI holds significant promise for developing novel neuromodulation strategies.

Conclusions:

  • Viewing therapeutic targets within brain networks, informed by dMRI and fMRI, represents a paradigm shift in surgical neuromodulation.
  • This advanced imaging approach is key to optimizing existing treatments and unlocking new therapeutic avenues for debilitating neurological and psychiatric disorders.
  • Continued research integrating neuroimaging and neuromodulation is essential for future advancements in functional neurosurgery.