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Updated: Jun 27, 2025

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
Improving Maternal Health and Birth Outcomes Through FreshRx: A Food-Is-Medicine Intervention
Dan Ferris1, Stephen Roll1, Jin Huang2
1Brown School at Washington University in St. Louis, St. Louis, MO, USA.
Purpose:
Food insecurity has far-reaching consequences for health and well-being, especially during pregnancy and postpartum periods. This study examines a food-is-medicine approach that aimed to reduce food insecurity, maternal stress, depression, anxiety, preterm labor, and low birthweight.
Design:
Pre-post interventional study of FreshRx: Nourishing Healthy Starts, a pregnancy focused food-is-medicine program led by a local hunger relief organization and obstetrics department.
Setting:
St. Louis, Missouri, a Midwestern U.S. city with higher-than-average infant mortality, low birthweight, and preterm birth rates.
Sample:
Participants (N = 125) recruited from a local obstetrics clinic had pregnancies earlier than 24 weeks gestation; spoke English; and were enrolled in Medicaid. At baseline, 67.0% reported very low food security and none reported high food security, while 34.7% indicated depressive symptoms.
Intervention:
FreshRx included weekly deliveries of fresh food meal kits, nutrition counseling and education, care coordination, and supportive services.
Measures:
18-Question U.S. Household Food Security Survey, Edinburgh Postnatal Depression Scale, birthweight, gestational age.
Analysis:
Single arm pre-post analysis.
Results:
Average gestational age of 38.2 weeks (n = 84) and birthweight of 6.7 pounds (n = 81) were higher than rates for the general population in the area. For study participants who completed a sixty-day post-partum assessment, 13% (n = 45) indicated maternal depression (P < .01).
Conclusion:
Food-is-medicine interventions may be an efficient, effective, and equitable tool for improving birth and maternal health outcomes.
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