Acute multiple brain infarctions associated with Streptococcus suis infection: a case report
Wenxin Wei1, Zhenhu Qiao1, Donghua Qin1
1Department of Neurology, Minzu Hospital Affiliated of Guangxi Medical University, Nanning, Guangxi, 530001, China.
BMC Infectious Diseases
|April 26, 2024
Summary
Streptococcus suis infection can cause serious illness, including meningitis and sepsis. This case highlights a rare complication: acute multiple brain infarctions, emphasizing the need for further research.
Area of Science:
- Infectious Diseases
- Neurology
- Public Health
Background:
- Streptococcus suis is a significant zoonotic pathogen causing meningitis, sepsis, and arthritis in humans.
- Human infections are reported globally, with a high prevalence in Asia.
- Hearing loss is a common sequela of Streptococcus suis meningitis.
Observation:
- A rare case of Streptococcus suis infection complicated by acute cerebral infarction is presented.
- A 69-year-old male patient experienced Streptococcus suis meningitis and sepsis.
- The patient developed multiple acute cerebral infarctions in the pons and bilateral frontotemporal parietal occipital lobes.
Findings:
- The patient presented with cognitive impairment, dyspraxia, and irritability post-treatment.
- This case represents a rare association between Streptococcus suis infection and acute multiple brain infarctions.
- Limited reports exist on cerebral infarction as a complication of Streptococcus suis infection.
Implications:
- This case underscores the potential neurological complications of Streptococcus suis infections.
- Further research is crucial to understand the pathogenesis and optimal treatment strategies for this rare complication.
- Increased awareness among clinicians is necessary for early diagnosis and management of Streptococcus suis-associated cerebral infarction.
Related Concept Videos
01:24Bacterial Meningitis
Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
01:18Viral Meningitis
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
01:29Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:26Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...