Related Experiment Video
Updated: Jun 27, 2025
06:39
Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
3.1K
Exploring the Relationship between Neuroticism and Perinatal Depressive Symptoms: Findings from a 2-Year, Multicenter
Melania Severo1,2, Annamaria Petito2, Antonio Ventriglio2
1Department of Humanistic Studies, University of Foggia, 71122 Foggia, Italy.
Brain Sciences
|April 27, 2024
Summary
High neuroticism in pregnant women is linked to increased depressive symptoms and lower wellbeing. Early assessment of neuroticism can help identify those needing psychological support for perinatal depression.
Area of Science:
- Psychiatry
- Psychology
- Obstetrics
Background:
- Neuroticism, a personality trait, is recognized as a risk factor for affective disorders.
- Perinatal depression poses significant risks to maternal and infant well-being.
Purpose of the Study:
- To investigate the relationship between neuroticism levels and psychological factors in pregnant women.
- To determine if neuroticism is associated with depressive symptoms during the perinatal period.
Main Methods:
- A cohort of 2631 pregnant women were assessed for depressive symptoms using the Edinburgh Postnatal Depression Scale (EPDS).
- Neuroticism was measured using the NEO Five Factor Inventory, alongside assessments of resilience, coping, attachment, and quality of life.
- Data were collected in the third trimester and at multiple points postpartum.
Main Results:
- Higher neuroticism scores correlated significantly with higher EPDS scores (depressive symptoms).
- Increased neuroticism was associated with lower psychological wellbeing, reduced resilience, and less active coping strategies.
- Women with higher neuroticism reported greater anxiety in relationships and higher self-blame.
Conclusions:
- Neuroticism is a significant associated factor for perinatal depression.
- Routine assessment of neuroticism in pregnant women is recommended for early identification and intervention.
- Clinical screening should facilitate timely referral to psychological or psychiatric services for at-risk individuals.
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