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Cancer and Cardiovascular Disease: The Conjoined Twins
Mohammad Zmaili1, Jafar Alzubi2, Motasem Alkhayyat3
1Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart, Vascular and Thoracic Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Cancer and cardiovascular disease significantly impact each other, yet are treated separately. This approach overlooks crucial connections and opportunities for improved patient care in both oncology and cardiology.
Area of Science:
- Cardio-oncology
- Interdisciplinary medicine
- Translational research
Background:
- Cancer and cardiovascular disease are leading global causes of mortality.
- These fields are increasingly interconnected, necessitating integrated care approaches.
- Current treatment paradigms often address cancer and cardiovascular disease independently.
Purpose of the Study:
- To elucidate the intricate relationship between cardiovascular disease and cancer.
- To highlight the impact of cardiovascular therapeutics on cancer patients.
- To advocate for a more unified approach to patient management.
Main Methods:
- Literature review of current research in oncology and cardiovascular medicine.
- Analysis of the downstream implications of cardiovascular disease on cancer.
- Examination of cardiovascular drug effects from an oncologic perspective.
Main Results:
- Cardiovascular disease and cancer share complex pathophysiological links.
- Independent treatment of one condition can negatively affect the other.
- Cardiovascular therapies may have unintended oncologic consequences.
Conclusions:
- An integrated approach is crucial for managing patients with both cancer and cardiovascular disease.
- Recognizing the interplay between these conditions improves patient outcomes.
- Further research into cardiovascular therapeutics' oncologic impact is warranted.
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