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Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
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The plasma membrane, a critical structure in cellular biology, houses an array of transporters, or carrier proteins, interspersed within its lipid bilayer. These proteins play a crucial role in solute transport through facilitated diffusion, a form of passive diffusion that uses transporters to move the molecules across the membrane.
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Transport Properties in Multicomponent Systems Containing Cyclodextrins and Nickel Ions.

Sónia I G Fangaia1,2,3, Daniela S A Silva3, Ana Messias1,4

  • 1Faculty of Medicine, Institute of Implantology and Prosthodontics, University of Coimbra, 3000-075 Coimbra, Portugal.

International Journal of Molecular Sciences
|April 27, 2024
PubMed
Summary

This study investigates nickel ion diffusion using cyclodextrins (CDs) to improve solubility and transport. Findings aid in understanding solute-solvent interactions and reducing nickel toxicity.

Keywords:
cyclodextrinsdiffusionmulticomponent systemsnickel ionstransport properties

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Area of Science:

  • Physical Chemistry
  • Solution Chemistry
  • Materials Science

Background:

  • Nickel ions pose potential toxicity concerns.
  • Enhancing solubility and transport of metal ions is crucial for various applications.
  • Cyclodextrins (CDs) are known for their ability to form inclusion complexes and modify solute properties.

Purpose of the Study:

  • To experimentally investigate the diffusion of nickel ions in aqueous solutions.
  • To evaluate the role of different cyclodextrins (alpha-CD, beta-CD, gamma-CD) as carrier molecules for nickel ions.
  • To understand the impact of cyclodextrins on the solubility, transport, and potential toxicity of nickel ions.

Main Methods:

  • Taylor dispersion method for measuring ternary mutual diffusion coefficients.
  • UV-vis spectroscopy for complementary system analysis.
  • Determination of physicochemical properties of nickel salts with CDs in aqueous solution.

Main Results:

  • Reported ternary mutual diffusion coefficients for nickel salts with alpha-CD, beta-CD, and gamma-CD at 298.15 K.
  • Obtained complementary information on solute-solvent interactions and diffusional transport mechanisms.
  • Provided data to estimate ion transport per mole of cyclodextrin.

Conclusions:

  • The study elucidates the diffusional behavior of nickel ions facilitated by cyclodextrins.
  • Understanding these interactions contributes to mitigating nickel ion toxicity.
  • The findings offer insights into solute-solvent interactions and transport mechanisms in aqueous systems.