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High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

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An Antimicrobial Copper-Plastic Composite Coating: Characterization and In Situ Study in a Hospital Environment.

Alexandre M Emelyanenko¹, Fadi S Omran¹, Maria A Teplonogova²

¹A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky Prospect 31, 119071 Moscow, Russia.

International Journal of Molecular Sciences

|April 27, 2024

Summary

Researchers developed a durable copper coating for electrical switch buttons using gas dynamic spray deposition. This antimicrobial coating significantly reduced microbial contamination in a hospital setting, offering a new defense against healthcare-associated infections.

Keywords:

ABS plastic antimicrobial effect bactericidal coatings copper healthcare-associated infections

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Area of Science:

Materials Science
Biotechnology
Infectious Disease Control

Background:

Healthcare-associated infections (HAIs) pose a significant threat, necessitating novel strategies for microbial control.
Electrical switch buttons are frequently touched surfaces, acting as potential reservoirs for pathogen transmission.
Existing antimicrobial solutions may lack durability or broad applicability.

Purpose of the Study:

To develop and evaluate an operationally durable copper coating with antimicrobial properties for electrical switch buttons.
To assess the efficacy of the copper coating in reducing microbial contamination in a real-world hospital environment.
To determine the potential of this technology in mitigating the spread of HAIs.

Main Methods:

Gas dynamic spray deposition of copper onto acrylonitrile butadiene styrene (ABS) plastic.
In situ studies comparing microbial contamination on copper-coated and standard buttons.
22-week environmental monitoring using swab analysis in a hospital setting.

Main Results:

A durable copper coating with an integral polymer film was successfully created on ABS plastic switch buttons.
Copper-coated buttons demonstrated a significant antimicrobial effect compared to standard buttons.
Environmental monitoring revealed a 2.7-fold reduction in microbial contamination frequency on copper-coated buttons over 22 weeks.

Conclusions:

The developed gas dynamic sprayed copper coating offers a durable and effective antimicrobial solution for plastic electrical switch buttons.
This technology presents a promising alternative for reducing microbial load on high-touch surfaces and combating HAIs.
The findings support the broader application of antimicrobial coatings in healthcare settings to enhance infection control measures.