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Updated: May 5, 2026

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Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
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Development of a Time Projection Chamber Readout with Hybrid Pixel Sensors for Beam Monitoring
Yingdong Song1,2,3, Haibo Yang2,3,4, Yuezhao Zhang2
1College of Physics and Electronic Engineering, Northwest Normal University, Lanzhou 730070, China.
Sensors (Basel, Switzerland)
|April 27, 2024
Summary
A new system, HiBeam-T, uses a time projection chamber (TPC) with CMOS sensors to track therapeutic carbon beams. This technology achieves high-resolution, real-time monitoring for precise cancer treatment delivery.
Area of Science:
- Medical Physics
- Particle Therapy
- Detector Technology
Background:
- Real-time monitoring of therapeutic particle beams is crucial for precise radiation delivery in cancer treatment.
- Existing methods may lack the resolution or speed required for optimal beam profile and position tracking.
Purpose of the Study:
- To introduce and evaluate HiBeam-T, a novel system for real-time monitoring of therapeutic carbon beams.
- To assess the performance and resolution of the HiBeam-T system.
Main Methods:
- Development of the HiBeam-T system, a time projection chamber (TPC) utilizing forty Topmetal-II- CMOS pixel sensors.
- The detector features a charge drift region and collection area with a sensitive area of 20 × 20 cm.
- Readout electronics include Readout Control Modules and a Clock Synchronization Module.
Main Results:
- The HiBeam-T system successfully monitored the position and profile of therapeutic carbon beams in real-time.
- Testing with an 80.55 MeV/u 12C6+ beam demonstrated a measurement resolution of 6.45 μm for the beam center under unsaturated conditions.
Conclusions:
- The HiBeam-T system provides high-resolution, real-time tracking capabilities for therapeutic carbon beams.
- This technology has the potential to enhance the precision and safety of particle therapy treatments.

