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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Related Experiment Video

Updated: May 6, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

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Precision Cardio-oncology: Update on Omics-Based Diagnostic Methods.

Ziyu Kuang1,2, Miao Kong1, Ningzhe Yan1,2

  • 1Oncology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Current Treatment Options in Oncology
|April 27, 2024
PubMed
Summary

Omics approaches offer new ways to understand and diagnose cancer treatment-related cardiovascular toxicity (CTR-CVT). Integrating diverse omics data can personalize monitoring and treatment for cancer patients, improving cardiovascular outcomes.

Keywords:
Cardio-oncologyCardiotoxicityOmicsPrecision medicine

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Area of Science:

  • Cardio-oncology
  • Biomarker discovery
  • Precision medicine

Background:

  • Cardio-oncology addresses cardiovascular events during cancer treatment.
  • Current management of cancer treatment-related cardiovascular toxicity (CTR-CVT) lacks detailed phenotypic data.
  • Precision medicine and omics offer potential for diagnosing CTR-CVT.

Purpose of the Study:

  • To review how omics approaches enhance CTR-CVT deep phenotyping.
  • To discuss the pros and cons of omics for CTR-CVT diagnosis.
  • To outline integrating multi-omics data for individualized patient care.

Main Methods:

  • Review of current literature on omics methodologies in cardio-oncology.
  • Analysis of deep phenotyping strategies for CTR-CVT.
  • Discussion of multi-omics data integration techniques.

Main Results:

  • Omics methodologies can significantly improve the understanding of CTR-CVT.
  • Various omics approaches have distinct advantages and limitations for CTR-CVT diagnosis.
  • Integrating multiple omics datasets is crucial for personalized monitoring and treatment.

Conclusions:

  • Omics approaches are vital for advancing cardio-oncology and CTR-CVT management.
  • Personalized monitoring and treatment strategies can be developed using integrated omics data.
  • This approach promises to reduce cardiovascular complications in cancer patients and survivors.