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Updated: Jun 27, 2025

Super-Resolution Imaging of Bacterial Secreted Proteins Using Genetic Code Expansion
Published on: February 10, 2023
T6SS-effector hunters uncover PIX: a novel delivery/marker domain
1Departamento de Microbiología, Facultad de Biología, Universidad de Sevilla, 41012, Seville, Spain.
Abstract:
Gram-negative bacteria use the T6SS to eject effectors into prey cells, aided by delivery domains. Recently uncovered by Carobbi et al., a new delivery domain, PIX, allowed the identification of hundreds of new effectors. They are order- and function-specific and exclusively orphan effectors, raising novel questions in the field.
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