Transient elastography with controlled attenuation parameter for the diagnosis of colorectal polyps in patients with nonalcoholic fatty liver disease
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View abstract on PubMed
Summary
This summary is machine-generated.High triglyceride (TG) and liver-controlled attenuation parameters (liver-CAP) levels are linked to colorectal polyps in nonalcoholic fatty liver disease (NAFLD) patients. Liver-CAP alone can effectively diagnose NAFLD with colorectal polyps.
Area Of Science
- Hepatology
- Gastroenterology
- Metabolic Syndrome
Background
- Nonalcoholic fatty liver disease (NAFLD) severity and lipid metabolism are associated with colorectal polyp development.
- Liver-controlled attenuation parameters (liver-CAPs) are established predictors for hepatic steatosis prognosis.
Purpose Of The Study
- To identify risk factors for colorectal polyps in NAFLD patients.
- To analyze liver-CAPs and develop a diagnostic model for colorectal polyps in NAFLD.
Main Methods
- Case-control study comparing patients with and without colorectal polyps (June 2021-April 2022).
- Analysis of triglyceride (TG) and liver-CAP levels.
- Receiver operating characteristic (ROC) curve analysis for diagnostic efficiency.
Main Results
- Patients with colorectal polyps had significantly higher median TG (1.74 vs 1.05 mmol/L) and liver-CAP (282 vs 254 dB/m) than controls (P < 0.05).
- TG and liver-CAP were independent risk factors for colorectal polyps (ORs 2.338 and 1.019, respectively; P < 0.05).
- Liver-CAP alone demonstrated diagnostic efficacy comparable to TG combined with liver-CAP (TG+CAP) (P > 0.05). A liver-CAP > 291 dB/m indicated higher polyp likelihood.
Conclusions
- Elevated TG and liver-CAP levels are significantly associated with colorectal polyps in NAFLD patients.
- Liver-CAP is a viable standalone diagnostic marker for NAFLD with colorectal polyps.
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