Related Experiment Video
Updated: Jun 27, 2025
06:19
Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia
Published on: September 27, 2024
210
Schizophrenia and Orthoptic Conditions: A Literature Review
Anna McBride1,2, Gemma Arblaster3
1University of Sheffield (BMedSci Orthoptics), UK.
The British and Irish Orthoptic Journal
|April 29, 2024
Summary
Patients with schizophrenia often experience ocular abnormalities, including strabismus and reduced vision. These visual disturbances may impact their quality of life and schizophrenia symptoms.
Area of Science:
- Ophthalmology
- Psychiatry
- Neuroscience
Background:
- Schizophrenia is a complex mental disorder with potential links to neurological and sensory deficits.
- Ocular abnormalities are increasingly recognized as a potential comorbidity in patients with schizophrenia.
Purpose of the Study:
- To review and synthesize existing literature on ocular abnormalities in schizophrenia patients.
- To determine the types and prevalence of orthoptic conditions in this population.
Main Methods:
- A narrative review of published studies was conducted.
- A systematic search of multiple databases identified 1,974 relevant studies from 1992 to 2022.
- Seventeen studies met the inclusion criteria for the final analysis.
Main Results:
- Schizophrenia patients showed a higher incidence of strabismus, reduced visual acuity, and impaired stereopsis compared to controls.
- Frequent eye movement abnormalities, such as reduced smooth pursuit gain and increased prosaccade latency, were reported.
- Reduced visual acuity correlated with negative schizophrenia symptoms and diminished quality of life.
Conclusions:
- Ophthalmologists and orthoptists should be aware of the increased prevalence of visual and eye movement abnormalities in schizophrenia.
- Further research is needed to explore the influence of these ocular conditions on schizophrenia symptoms and the potential impact of medication.
Related Concept Videos
01:27Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
598
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
598
01:29Psychological and Sociocultural Causes of Schizophrenia
84
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
84
01:29Biological Causes of Schizophrenia
55
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
55
01:22Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
01:17Schizophrenia
76
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
76
01:28Psychosis and Antipsychotic Drugs: Overview
244
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
244