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Use of a Rat Model to Study Ventral Abdominal Hernia Repair
Published on: October 2, 2017
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Ventral Hernia Reconstruction with GORE ENFORM Biomaterial
Andrew W Hollins1, Andrew Atia1, Gloria Zhang1
1Division of Plastic, Maxillofacial, and Oral Surgery, Department of Surgery, Duke University Health System, Durham, NC, USA.
Plastic Surgery (Oakville, Ont.)
|April 29, 2024
Summary
This study evaluated GORE® ENFORM Biomaterial™, a new degradable mesh for ventral hernia repair. While some surgical site occurrences were noted, the mesh shows promise for complex hernia reconstructions.
Area of Science:
- Surgical Innovation
- Biomaterials Science
- Hernia Surgery
Background:
- Ventral hernia repair (VHR) is a common surgical procedure.
- Degradable mesh is preferred for high-risk patients undergoing VHR.
- GORE® ENFORM Biomaterial™ is a novel biosynthetic degradable mesh with limited clinical outcome data.
Purpose of the Study:
- To report the initial clinical outcomes of ventral hernia repair using GORE® ENFORM Biomaterial™.
- To assess surgical site occurrences, hernia recurrence, and patient-reported outcomes.
Main Methods:
- A single-surgeon case series included 15 patients undergoing VHR with GORE® ENFORM Biomaterial™.
- Data collected included patient comorbidities, hernia characteristics, and postoperative outcomes.
- Patient-Reported Outcomes Measurement Information System (PROMIS) and HerQLes surveys were utilized.
Main Results:
- The average follow-up was 315 days.
- 26.7% of patients experienced surgical site occurrences, including 4 surgical site infections.
- One hernia recurrence was observed, and two patients required mesh removal.
Conclusions:
- This is the first clinical study detailing outcomes for VHR using ENFORM mesh.
- ENFORM mesh presents a viable option for complex ventral hernia reconstructions.
- Further investigation is warranted to fully elucidate the long-term efficacy and safety profile.
