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Related Experiment Video

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Rat Model of Adhesive Capsulitis of the Shoulder
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Adhesive Capsulitis Following Improper Tetanus-Diphtheria (Td) Booster Administration.

David Weinberg1, Mackinzie McDaniel1, Jason Pan1

  • 1Physical Medicine and Rehabilitation, University of Pennsylvania, Philadelphia, USA.

Cureus
|April 29, 2024
PubMed
Summary
This summary is machine-generated.

Adhesive capsulitis, a rare shoulder complication, can occur after improper vaccine injection into the deltoid muscle. This case highlights a potential link between tetanus-diphtheria (Td) vaccination errors and this debilitating condition.

Keywords:
adhesive capsulitisbooster vaccinediphtheriaimproper vaccinationsirvatdtetanusvaccination

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Area of Science:

  • Orthopedics
  • Immunology
  • Sports Medicine

Background:

  • Adhesive capsulitis is a shoulder condition characterized by stiffness and pain.
  • Shoulder Injury Related to Vaccine Administration (SIRVA) encompasses various shoulder pathologies resulting from incorrect vaccine injection.
  • Improper intramuscular deltoid vaccine administration can lead to needle placement errors, affecting joint structures.

Observation:

  • A previously healthy middle-aged female developed left shoulder pain and stiffness after a tetanus-diphtheria (Td) booster vaccination.
  • The patient reported the injection was administered higher than usual in the deltoid muscle.
  • Symptoms progressed over two weeks, leading to significant loss of shoulder range of motion.

Findings:

  • The patient was diagnosed with adhesive capsulitis four months after symptom onset.
  • This represents the first reported case of adhesive capsulitis following an improper tetanus-diphtheria (Td) vaccine administration.
  • The patient was referred for physical therapy but was lost to follow-up, leaving recovery status uncertain.

Implications:

  • This case suggests a potential association between incorrect vaccine administration technique and the development of adhesive capsulitis.
  • Further research is needed to understand the temporal course and recovery patterns of vaccine-induced adhesive capsulitis compared to classic adhesive capsulitis.
  • Clinicians should be aware of SIRVA as a differential diagnosis in patients presenting with shoulder pain and stiffness post-vaccination.