Related Experiment Video

Updated: May 13, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.5K

Acute Kidney Injury After Percutaneous Coronary Intervention Guided by Intravascular Ultrasound

Minh Tran Duc1, Thai Nguyen Quoc2, Bach Yen T Nguyen1

  • 1Cardiology, Tam Anh Hospital, Ha Noi, VNM.

Cureus
|April 29, 2024
PubMed

Insights

Intravascular ultrasound guidance significantly reduces contrast-induced acute kidney injury (CI-AKI) in patients undergoing percutaneous coronary intervention (PCI). This imaging technique offers a safer alternative to angiography alone, especially for high-risk patients.

Area of Science:

  • Cardiology
  • Nephrology
  • Medical Imaging

Background:

  • Contrast-induced acute kidney injury (CI-AKI) is a significant complication following percutaneous coronary intervention (PCI).
  • Angiography guidance in PCI may lead to higher contrast volumes and increased risk of CI-AKI.
  • Intravascular ultrasound (IVUS) offers detailed real-time imaging during PCI procedures.

Purpose of the Study:

  • To evaluate the effectiveness of intravascular ultrasound (IVUS) guidance in reducing CI-AKI incidence compared to traditional angiography guidance.
  • To assess the safety and impact of IVUS on contrast volume administration during PCI.

Main Methods:

  • A prospective cohort study involving 99 patients undergoing PCI at Vietnam National Heart Institute - Bach Mai Hospital.
  • Patients were divided into two groups: IVUS-guided PCI (33 patients) and angiography-guided PCI (66 patients).
  • The primary endpoint was the incidence of acute kidney injury during hospitalization.

Main Results:

  • The IVUS-guided group used significantly less contrast volume (95.2 ± 37.1 mL) compared to the angiography-guided group (133.0 ± 36.0 mL) (P < 0.0001).
  • The incidence of CI-AKI was significantly lower in the IVUS-guided group (0.0%) compared to the angiography-guided group (12.12%) (P = 0.049).

Conclusions:

  • Intravascular ultrasound (IVUS) is a safe and effective imaging tool for guiding percutaneous coronary intervention (PCI).
  • IVUS guidance significantly reduces the incidence of contrast-induced acute kidney injury (CI-AKI) compared to angiography alone.
  • Patients at high risk for CI-AKI may particularly benefit from IVUS-guided PCI.

Keywords:
contrast-induced acute kidney injuryintravascular ultrasound (ivus)iodinated contrastivus-guided pciprimary percutaneous coronary intervention (pci)

More Related Videos

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

2.2K
Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography03:19

Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

Published on: June 21, 2024

1.1K

Related Concept Videos

Vascular Spasm01:16

Vascular Spasm

The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last for...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...