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Computed Tomography01:10

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Automated abdominal CT contrast phase detection using an interpretable and open-source artificial intelligence

Eduardo Pontes Reis1,2,3, Louis Blankemeier4, Juan Manuel Zambrano Chaves5,6

  • 1Department of Radiology, Stanford University, Stanford, CA, USA. eduardo.reis@einstein.br.

European Radiology
|April 29, 2024
PubMed
Summary
This summary is machine-generated.

An open-source artificial intelligence (AI) algorithm accurately identifies contrast phases in abdominal CT scans. This tool demonstrates strong performance in both internal and external validation, improving diagnostic capabilities.

Keywords:
AbdomenArtificial intelligenceContrast mediaMachine learningRadiomics

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Radiology

Background:

  • Accurate contrast phase identification in abdominal CT scans is crucial for subsequent AI applications and biomarker quantification.
  • Existing methods for phase determination, such as Digital Imaging and Communications in Medicine (DICOM) labels, can be inaccurate.
  • There is a need for reliable and automated methods to detect contrast phases.

Purpose of the Study:

  • To develop and validate an open-source artificial intelligence (AI) algorithm for accurate detection of contrast phases in abdominal CT scans.
  • To create an interpretable AI model that can generalize across different datasets.

Main Methods:

  • A retrospective study developed an AI algorithm using 739 abdominal CT exams.
  • Deep learning-based segmentation (TotalSegmentator) and radiomics features were employed.
  • A gradient-boosting classifier was trained to identify four contrast phases: non-contrast, arterial, venous, and delayed.

Main Results:

  • The AI algorithm achieved 92.3% accuracy and 90.7% F1 score in internal validation.
  • External validation on the VinDr-Multiphase CT dataset showed 90.1% accuracy and 82.6% F1 score.
  • Shapley analysis identified renal and vascular radiodensity as key features for classification.

Conclusions:

  • The developed open-source AI algorithm accurately detects contrast phases in abdominal CT scans.
  • The algorithm demonstrates strong generalization capabilities through robust internal and external validation.
  • This AI tool can enhance downstream AI applications, biomarker quantification, and improve diagnostic accuracy and access.