[Ischemic stroke due to paradoxical embolism through pulmonary arteriovenous malformation in a young patient]

Matías J Alet1, Hernán Bertoni2, Sebastián F Ameriso1

  • 1Centro Integral de Neurología Vascular, FLENI, Buenos Aires, Argentina.

Medicina
|April 29, 2024
PubMed

Insights

Pulmonary arteriovenous malformations (PAVMs) can cause paradoxical embolism leading to ischemic stroke, particularly in young adults. Successful endovascular treatment of PAVM resolved the stroke in a 34-year-old woman.

Area of Science:

  • Cardiology
  • Neurology
  • Radiology

Background:

  • Paradoxical embolism is a rare cause of ischemic stroke.
  • Pulmonary arteriovenous malformations (PAVMs) are abnormal connections between pulmonary arteries and veins.

Observation:

  • A 34-year-old woman presented with ischemic stroke.
  • Transcranial Doppler showed contrast passage in cerebral arteries.
  • Intracardiac ultrasound ruled out patent foramen ovale.

Findings:

  • Pulmonary CT angiography confirmed an isolated PAVM.
  • The patient underwent successful endovascular embolization for the PAVM.

Implications:

  • PAVM should be considered in the etiological diagnosis of ischemic stroke, especially in young patients.
  • Endovascular embolization is the preferred treatment for significant PAVMs.
  • Periodic follow-up imaging is recommended to monitor PAVMs.

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