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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
[Ischemic stroke due to paradoxical embolism through pulmonary arteriovenous malformation in a young patient]
Matías J Alet1, Hernán Bertoni2, Sebastián F Ameriso1
1Centro Integral de Neurología Vascular, FLENI, Buenos Aires, Argentina.
Abstract:
Paradoxical embolism due to an isolated pulmonary arteriovenous malformation (PAVM) is a rare cause of ischemic stroke. PAVMs are abnormal high-flow connections between pulmonary arteries and veins, diverting deoxygenated blood into the systemic circulation and they represent a less common source of paradoxical embolisms, especially in young individuals. Endovascular embolization is the preferred treatment for clinically significant PAVMs. We present the case of a 34-year-old woman with a left thalamic ischemic stroke. Severe contrast passage was detected in cerebral arteries through transcranial Doppler. Intracardiac ultrasound did not reveal a patent foramen ovale, prompting further investigation with pulmonary CT angiography, confirming the presence of PAVM. The patient underwent successful endovascular treatment. It is essential to consider PAVM in the etiological diagnosis of ischemic stroke, especially in young patients with signs of abnormal right-to-left communication. Periodic follow-up imaging is recommended to assess potential recurrence or changes in PAVM, emphasizing the importance of appropriate management of these malformations.
Insights
Pulmonary arteriovenous malformations (PAVMs) can cause paradoxical embolism leading to ischemic stroke, particularly in young adults. Successful endovascular treatment of PAVM resolved the stroke in a 34-year-old woman.
Area of Science:
- Cardiology
- Neurology
- Radiology
Background:
- Paradoxical embolism is a rare cause of ischemic stroke.
- Pulmonary arteriovenous malformations (PAVMs) are abnormal connections between pulmonary arteries and veins.
Observation:
- A 34-year-old woman presented with ischemic stroke.
- Transcranial Doppler showed contrast passage in cerebral arteries.
- Intracardiac ultrasound ruled out patent foramen ovale.
Findings:
- Pulmonary CT angiography confirmed an isolated PAVM.
- The patient underwent successful endovascular embolization for the PAVM.
Implications:
- PAVM should be considered in the etiological diagnosis of ischemic stroke, especially in young patients.
- Endovascular embolization is the preferred treatment for significant PAVMs.
- Periodic follow-up imaging is recommended to monitor PAVMs.
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