Related Experiment Video
Updated: Jun 27, 2025
08:34
Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
8.6K
[Brain abscess due to Aggregatibacter aphrophilus].
1Departamento de Medicina Interna. Hospital Universitario Fundación Sanatorio Güemes, Buenos Aires, Argentina.
Medicina
|April 29, 2024
Summary
Aggregatibacter aphrophilus, a rare cause of brain abscess, typically originates from oropharyngeal flora. This case highlights a rare instance of invasive bacteremia leading to a brain abscess in an immunocompetent adult.
Area of Science:
- Neurology
- Infectious Diseases
- Microbiology
Background:
- Brain abscesses are typically bacterial, but Aggregatibacter aphrophilus (A. aphrophilus) is an uncommon causative agent.
- A. aphrophilus, a HACEK group bacterium, is part of normal oropharyngeal and respiratory flora, rarely causing invasive infections.
Observation:
- A 64-year-old male presented with headache, hemianopsia, and seizures.
- Imaging and culture confirmed a brain abscess due to A. aphrophilus.
Findings:
- This case represents a rare instance of brain abscess caused by A. aphrophilus.
- The infection was associated with typical risk factors such as poor dental hygiene.
Implications:
- This case underscores the importance of considering A. aphrophilus in brain abscess etiology, even in immunocompetent individuals.
- Optimal treatment involves abscess drainage and targeted antibiotic therapy, ideally beta-lactams.
