Microjet wound therapy versus sharp debridement on wound size reduction: a pilot randomised controlled trial

Area of Science:

• Wound healing research
• Medical technology innovation

Background:

• Chronic wounds present treatment challenges due to varying efficacy, speed, cost, and pain.
• Current treatments aim to stimulate the wound healing cascade.

Purpose of the Study:

• To assess the feasibility of a novel microjet wound therapy technology.
• To compare microjet therapy outcomes against standard sharp debridement for chronic wounds.

Main Methods:

• A randomized, controlled, open-label pilot study.
• 13 patients were assigned to microjet therapy (n=5) or standard mechanical debridement (n=8).
• Study conducted in an outpatient wound clinic from March 2022 to May 2023.

Main Results:

• Insufficient power to detect significant differences, but a trend towards faster wound area reduction was observed with microjet therapy.
• Microjet therapy showed potential for alleviating patient anxiety.
• Potential cost savings identified due to reduced treatment time and fewer consultations.

Conclusions:

• Microjet therapy may promote faster healing in hard-to-heal wounds.
• The study provides a feasibility basis for larger, multicenter trials.
• Further research is warranted to confirm the efficacy and benefits of microjet wound therapy.