Bile duct obstruction by villous papilloma of duodenum

Two cases of peri-ampullary villous adenomas involving the common bile duct are reported. The pathology of benign duodenal tumours is discussed, and the possibility of common bile duct involvement, albeit uncommon, is stressed. Obtaining an endoscopic histologic diagnosis is important in planning appropriate operative treatment. Although benign, these tumours should be removed; they are a cause of serious symptoms and have proven premalignant potential. Endoscopic removal is usually not possible. Endoscopy for dyspepsia should include examination of the second part of duodenum, to avoid overlooking duodenal tumours.