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Medicinal Plants in the Treatment of Myocardial Infarction Disease: A Systematic Review
Anamika Rathore1, Anuj Kumar Sharma1, Yogesh Murti2
1Department of Pharmacology, Rajiv Academy for Pharmacy, Mathura, Uttar Pradesh, India.
Insights
Herbal remedies show promise for treating myocardial infarction (MI). This review identified 140 plants, with flavonoids and glucosides being key compounds, highlighting natural substances for future MI treatments.
Area of Science:
- Cardiovascular Medicine
- Pharmacognosy
- Phytochemistry
Background:
- Myocardial infarction (MI), or heart attack, results from interrupted blood flow to the heart muscle.
- MI can range from silent to life-threatening, causing hemodynamic instability and mortality.
- Herbal remedies are increasingly recognized for their safety and accessibility in managing MI.
Purpose of the Study:
- To review medicinal plants and phytochemicals used in myocardial infarction (MI) treatment.
- To evaluate the potential of natural compounds in developing novel herbal MI therapies.
Main Methods:
- A comprehensive literature search was conducted across major scientific databases.
- Databases included Web of Science, Google Scholar, PubMed, Sci Finder, Reaxys, and Cochrane.
Main Results:
- 140 plant species from 12 families were identified for their use in MI.
- Data abstracted included plant families, parts used, chemical constituents, and dosages.
- Fabaceae and Asteraceae were dominant families; flavonoids, glucosides, and alkaloids were prevalent compounds.
Conclusions:
- Natural products, particularly flavonoids and glucosides, show significant potential for MI treatment.
- This review provides a foundation for developing evidence-based herbal medicines for cardiovascular health.
Background:
Myocardial infarction (MI), also referred to as a "heart attack," is brought on by a partial or total interruption of blood supply to the myocardium. Myocardial infarction can be "silent," go undiagnosed, or it can be a catastrophic occurrence that results in hemodynamic decline and untimely death. In recent years, herbal remedies for MI have become effective, secure, and readily accessible.
Objective:
The purpose of this review was to examine the medicinal plants and phytochemicals that have been used to treat MI in order to assess the potential contribution of natural substances to the development of herbal MI treatments.
Methodology:
A literature search was employed to find information utilizing electronic databases, such as Web of Science, Google Scholar, PubMed, Sci Finder, Reaxys, and Cochrane.
Results:
The identification of 140 plants from 12 families led to the abstraction of data on the plant families, parts of the plant employed, chemical contents, extracts, model used, and dose.
Conclusion:
The majority of the MI plants, according to the data, belonged to the Fabaceae (11%) and Asteraceae (9%) families, and the most prevalent natural components in plants with MI were flavonoids (43%), glucosides (25%), alkaloids (23%), phenolic acid (19%), saponins (15%), and tannins (12%).
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