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Updated: Jun 27, 2025

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Effectiveness of onabotulinumtoxin A for refractory overactive bladder with cough-associated detrusor overactivity
Chie Nakai1, Kosei Miwa1, Akane Yamaguchi1
1Department of Urology Japanese Red Cross Gifu Hospital Gifu Japan.
Introduction:
We report a case of refractory overactive bladder with cough-associated detrusor overactivity treated by onabotulinumtoxin A.
Case Presentation:
A 79-year-old woman who underwent mid-urethral sling surgery 8 years ago complained mainly of urinary incontinence following abdominal pressure. Various medicines to treat overactive bladder symptoms were ineffective. Cystometry revealed cough-associated detrusor overactivity. Onabotulinumtoxin A injections in her bladder improved subjective symptoms, and cough-associated detrusor overactivity disappeared on cystometry.
Conclusions:
Onabotulinumtoxin A injection effectively resolved refractory overactive bladder with urgency urinary incontinence due to cough-associated detrusor overactivity.
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