Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.6K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.6K
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.8K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simultaneous Nucleation-Nanowelding Generates Uniform Plasmonic Au-Au Nanojunctions in 3D-Welded Gold Nanostructures.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Metabolic transcriptomic subtyping defines distinct immunogenomic and clinical landscapes in non-small cell lung cancer.

NPJ precision oncology·2026
Same author

Food literacy as a moderator in the relationship between food security and dietary diversity among adults in Seoul: based on the 2021-2023 Seoul Food Survey.

Nutrition research and practice·2026
Same author

Evaluation of 2-methyl-4-isothiazolin-3-one-induced human pulmonary toxicity using integrated air-liquid-interface and a lung-on-chip.

Respiratory research·2026
Same author

Overcoming Biological Barriers and Drug Resistance Through Next-Generation Nanotherapeutic Delivery in Gastric Cancer.

Cells·2026
Same author

Rhizomes as Multi-Target Pharmacological Platforms Against Tauopathy: Neuro-Metabolic Crosstalk, Drug-Likeness, and Translational Challenges.

Pharmaceuticals (Basel, Switzerland)·2026

Related Experiment Video

Updated: May 2, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.3K

Microfluidics for disease diagnostics based on surface-enhanced raman scattering detection.

Xiangdong Yu1, Sohyun Park1, Sungwoon Lee1

  • 1Department of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.

Nano Convergence
|April 30, 2024
PubMed
Summary

This review explores surface-enhanced Raman scattering (SERS) microfluidic systems for disease diagnosis. These integrated technologies offer high-sensitivity detection for advanced biomedical applications and clinical diagnostics.

Keywords:
Biomedical diagnosticsLab-on-a-chipMicrofluidicsOn-chip detectionSurface-enhanced Raman scattering

More Related Videos

Fabricating a UV-Vis and Raman Spectroscopy Immunoassay Platform
09:02

Fabricating a UV-Vis and Raman Spectroscopy Immunoassay Platform

Published on: November 10, 2016

10.4K
Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.5K

Related Experiment Videos

Last Updated: May 2, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.3K
Fabricating a UV-Vis and Raman Spectroscopy Immunoassay Platform
09:02

Fabricating a UV-Vis and Raman Spectroscopy Immunoassay Platform

Published on: November 10, 2016

10.4K
Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.5K

Area of Science:

  • Analytical Chemistry
  • Biomedical Engineering
  • Nanotechnology

Background:

  • Microfluidic systems enable precise manipulation of small liquid volumes.
  • Surface-enhanced Raman scattering (SERS) provides highly sensitive molecular detection.
  • Integrating these technologies offers potential for advanced diagnostic tools.

Purpose of the Study:

  • To review diverse microfluidic systems using SERS detection for disease diagnosis.
  • To explore the principles and applications of SERS-based microfluidic devices over the past two decades.
  • To identify areas for future development in clinical diagnostics.

Main Methods:

  • Investigation of continuous-flow, microarray-embedded, droplet, digital droplet, and gradient microfluidic channels.
  • Analysis of SERS principles within microfluidic platforms.
  • Examination of applications in biomedical diagnostics.

Main Results:

  • Documented various SERS-based microfluidic device designs and operational principles.
  • Highlighted the expansion of analytical capabilities using integrated SERS and microfluidics.
  • Demonstrated applications in the field of biomedical diagnostics.

Conclusions:

  • SERS-based microfluidic technologies show significant promise for disease diagnosis.
  • Further development is needed to translate these systems into practical clinical applications.
  • The integration of SERS and microfluidics enhances sensitivity and analytical power for diagnostics.