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Association between kidney stones and life's essential 8: a population-based study
Yuan-Zhuo Du1,2, Biao Guo1,2, Hong-Ji Hu1,2
1Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China.
World Journal of Urology
|April 30, 2024
Summary
Higher cardiovascular health, measured by Life's Essential 8 (LE8), is linked to a lower risk of developing kidney stones. Improving cardiovascular health may help prevent kidney stones.
Area of Science:
- Cardiology
- Nephrology
- Public Health
Background:
- Kidney stones are strongly associated with cardiovascular disease (CVD).
- Cardiovascular health (CVH) assessment has been updated with Life's Essential 8 (LE8).
Purpose of the Study:
- To investigate the correlation between kidney stones and LE8 among US adults.
- To examine the relationship between kidney stone occurrence and overall CVH.
- To explore the association between kidney stones and LE8 subscale scores.
Main Methods:
- Analysis of data from the 2007-2018 National Health and Nutrition Examination Survey.
- Used LE8 scores (0-100) categorized into low, moderate, and high CVH.
- Employed multivariate logistic regression and restricted cubic spline models.
Main Results:
- A total of 14,117 participants were analyzed, with a mean LE8 score of 69.70.
- Higher LE8 scores showed an inverse association with kidney stone likelihood (OR 0.81 per 10-point increase).
- A non-linear dose-response pattern was observed, consistent across health behaviors and factors.
Conclusions:
- LE8 scores and subscale scores demonstrated a significant inverse correlation with kidney stone occurrence.
- Optimal CVH adherence may be a viable strategy for kidney stone prevention.
- Findings suggest a link between cardiovascular wellness and kidney stone risk reduction.
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