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Updated: Jun 27, 2025

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Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
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Paradigm shift required for translational research on the brain.
Jong Hyuk Yoon1, Dongha Lee2, Chany Lee2
1Neurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu, 41062, Republic of Korea. jhyoon@kbri.re.kr.
Experimental & Molecular Medicine
|April 30, 2024
Summary
Brain research faces unique challenges due to complexity and interdisciplinary gaps, slowing progress. Recent advances in neuroimaging, multiomics, and AI enable large-scale, patient-centered studies, promising significant breakthroughs.
Area of Science:
- Neuroscience
- Biomedical Research
Background:
- Historical brain research faced challenges from high complexity and limited interdisciplinary communication.
- These factors contributed to slower development compared to other biomedical fields.
Purpose of the Study:
- To review conventional biomedical research aspects.
- To discuss the future trajectory of brain biomedical research.
Main Methods:
- Emerging high-throughput analysis tools.
- Integration of neuroimaging, multiomics, and artificial intelligence (AI).
- Facilitation of interdisciplinary cooperative studies.
Main Results:
- A paradigm shift towards patient-centered, large-scale brain research is occurring.
- New technologies are driving significant advances in translational research.
- Interdisciplinary collaboration offers solutions to complex biomedical questions.
Conclusions:
- The future of brain biomedical research is characterized by technological integration and collaborative approaches.
- These advancements are poised to accelerate understanding of the brain and treatment of its diseases.
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