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High prevalence of erectile dysfunction in men with hyperthyroidism: a meta-analysis
Xiaowen Liu1, Yanling Wang2, Li Ma2
1Hunan Provincial Key Laboratory of Regional Hereditary Birth Defects Prevention and Control, Changsha Hospital for Maternal & Child Health Care, Hunan Normal University, Changsha, China. 124821877@qq.com.
BMC Endocrine Disorders
|April 30, 2024
Summary
Men with hyperthyroidism have a significantly increased risk of developing erectile dysfunction (ED). This study highlights a strong association between hyperthyroidism and ED, impacting men's health.
Area of Science:
- Endocrinology
- Men's Health
- Sexual Medicine
Background:
- Hyperthyroidism, a condition of overactive thyroid hormone production, is linked to various systemic effects.
- Erectile dysfunction (ED) is a common condition affecting men's sexual health and quality of life.
Purpose of the Study:
- To evaluate the association between hyperthyroidism and the risk of developing erectile dysfunction (ED).
Main Methods:
- A comprehensive literature search was performed across major databases (PubMed, Embase, Cochrane, Web of Science).
- Study quality was assessed using the Newcastle-Ottawa Scale.
- A meta-analysis of four relevant studies involving 25,519 men was conducted.
Main Results:
- The overall prevalence of ED in hyperthyroid patients was 31.1%.
- In uncomplicated hyperthyroidism, ED incidence was 21.9%.
- A combined odds ratio of 1.73 (95% CI [1.46-2.04], p<.00001) indicated a significantly higher risk of ED in men with hyperthyroidism.
Conclusions:
- Hyperthyroidism is associated with a higher incidence of erectile dysfunction.
- These findings are crucial for healthcare providers managing patients with hyperthyroidism.
- This information can guide discussions on appropriate ED treatment strategies for affected individuals.
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