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A colorimetric approach for monitoring the reduction of platinum(iv) complexes in aqueous solution
Shitong Huang1, Jevon W Marsh1, Jhanelle R G White2
1Chemistry Research Laboratory, University of Oxford Mansfield Road OX1 3TA UK adam.sedgwick@kcl.ac.uk.
Abstract:
We report the synthesis of 4-nitrophenyl (4-NP) functionalised Pt(iv) complexes as a colorimetric strategy for monitoring Pt(iv) reduction in aqueous solution. Treatment of each 4-NP functionalised Pt(iv) complex with the biological reductant sodium ascorbate led to a colour change from clear to yellow, which was attributed to the reduction of Pt(iv) to Pt(ii) and simultaneous release of 4-nitroaniline. Trends in reduction profiles and a photocatalysed reduction for each Pt(iv) complex were observed.
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