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A comprehensive study on venous endovascular management and stenting in deep veins occlusion and stenosis: A review
Javad Salimi1, Fatemeh Chinisaz2, Seyed Amir Miratashi Yazdi1
1Department of Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Insights
Venous stenting is a promising treatment for post-thrombotic syndrome (PTS) and non-thrombotic iliac vein lesions (NIVL). This review synthesizes current evidence to guide future protocol development for venous stenting in these conditions.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Medical Device Technology
Background:
- Deep venous disease encompasses post-thrombotic syndrome (PTS) and non-thrombotic iliac vein lesions (NIVL).
- Venous hypertension, caused by stenosis or obstruction, is the primary driver of symptoms in PTS and NIVL.
- Venous stenting presents a minimally invasive treatment option for NIVL and PTS with high patency rates.
Purpose of the Study:
- To comprehensively review influencing factors, diagnostic imaging, stent characteristics, and interventions for venous stenting in PTS and NIVL.
- To identify challenges and analyze outcomes related to venous stenting in patients with PTS and NIVL.
- To provide insights for developing validated protocols and guidelines for venous stenting in deep venous disease.
Main Methods:
- Systematic review of published literature from 2008 to 2023.
- Keywords used: "venous stenting", "PTS", "NIVL", "occlusion", and "stenosis".
- Databases searched: PubMed, MEDLINE, and Google Scholar.
Main Results:
- Analysis of 476 studies focusing on patency rates, complications, and quality of life.
- Significant variability in approaches and outcomes observed.
- Absence of a validated protocol or guideline for venous stenting in PTS and NIVL patients.
Conclusions:
- Current literature highlights the potential of venous stenting for PTS and NIVL.
- The lack of standardized protocols necessitates further research and guideline development.
- This review offers a foundation for researchers aiming to establish best practices in venous stenting.
Background:
Patients with deep venous disease can be classified into two distinct categories: those with disease resulting from known deep vein thrombosis (DVT), which may subsequently lead to post-thrombotic syndrome (PTS), and those with disease caused by compressive factors or non-thrombotic iliac vein lesions (NIVL). The major factor causing the symptoms in patients with PTS and NIVL is venous hypertension which happens due to venous stenosis or venous obstruction. Nowadays Venous stenting offers a noninvasive approach for treatment of NIVL and PTS demonstrating high patency rate.
Methods:
We comprehensively reviewed relevant published papers from 2008 to 2023 that surveyed various influencing factors including the site of occlusion and etiology of occlusions, proper diagnostic imaging, ideal characteristics of venous stents, different dedicated venous stents, pre-operative, concomitant, and post-operative interventions and factors that challenge stenting in both PTS and NIVL patients. The papers were identified by searching the keywords "venous stenting", "PTS", "NIVL", "occlusion", and "stenosis" in PubMed central library MEDLINE and Google Scholar.
Results:
Patency rates, post-stent complications, and relevant data according to the patient's quality of life were included and analyzed from 476 identified studies. There is no validated protocol and guideline for using stents in patients with PTS and NIVL.
Conclusion:
As there is no validated protocol and guideline for using stents in patients with PTS and NIVL, our study may provide comprehensive information to assist researchers interested in writing the protocol and give them insight.
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