Asia-Pacific consensus on long-term and sequential therapy for osteoporosis

Area of Science:

• Bone Metabolism and Osteoporosis Research
• Geriatric Medicine
• Pharmacology

Background:

• Osteoporosis is a chronic condition requiring effective long-term management.
• Optimal fracture prevention necessitates a comprehensive and individualized therapeutic approach.

Purpose of the Study:

• To present the Asia-Pacific consensus on long-term and sequential osteoporosis therapy.
• To provide evidence-based recommendations for managing osteoporosis and preventing fractures.

Main Methods:

• A panel of experts synthesized current literature and clinical expertise.
• The review focused on long-term treatment goals, first-line therapies for high-risk individuals, and sequential anabolic-antiresorptive agent integration.

Main Results:

• Consensus reached on 12 statements for osteoporosis management.
• Anabolic agents recommended as first-line for very high-risk patients, followed by antiresorptives.
• Strategies for managing treatment complications and inadequate responses were outlined.

Conclusions:

• The consensus offers a cost-effective fracture prevention strategy for the Asia-Pacific region.
• Emphasis on shared decision-making and integration of services like fracture liaison.
• Provides a valuable guide for healthcare professionals in evolving osteoporosis care.