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Prolonged fever with pancytopenia and massive hepatosplenomegaly
Roopa Sharma1, Abhishek Yadav1, Bhavana Mastebhakti1
1Department of Internal Medicine, Maulana Azad Medical College, New Delhi 110002, India.
Abstract:
Prolonged fever with pancytopenia and hepatosplenomegaly is a clinical entity frequently encountered by physicians. The diagnosis of such cases is challenging due to the diversity of differential diagnoses. Hepatosplenic T-cell lymphoma is a rare and aggressive type of non-Hodgkin lymphoma that can present with massive hepatosplenomegaly, pancytopenia and prolonged fever. Most of the patients are young men and the majority are associated with chronic immunosuppression. We report a 40-year-old immunocompetent woman with prolonged fever and pancytopenia due to hepatosplenic T-cell lymphoma.
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