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Updated: Jun 27, 2025
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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
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Trends in infectious spondylitis from 2000 to 2020
Shinji Tanishima1, Tokumitsu Mihara2, Chikako Takeda2
1Division of Orthopedic Surgery, Department of Sensory and Motor Organs, School of Medicine, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago, Tottori, 683-8504, Japan. shinjit@tottori-u.ac.jp.
Summary
Infectious spondylitis trends show a decrease in resistant bacteria like MRSA and an increase in indigenous oral and gut bacteria over two decades. This shift impacts treatment strategies for spinal infections.
Area of Science:
- Spinal infections
- Epidemiology of infectious diseases
- Microbiology of bone infections
Background:
- Infectious spondylitis is a serious condition affecting the spine.
- Understanding trends in causative organisms is crucial for effective management.
- Changes in microbial resistance and common pathogens over time require investigation.
Purpose of the Study:
- To analyze the epidemiological trends of infectious spondylitis over a 20-year period.
- To compare causative organisms, patient demographics, and infection sources between two distinct time intervals (2000-2009 and 2010-2020).
Main Methods:
- Retrospective analysis of 157 infectious spondylitis cases from 2000 to 2020.
- Cases divided into two groups: 2000-2009 (n=82) and 2010-2020 (n=75).
- Comparison of patient age, sex, causative organism, and infection source between groups.
Main Results:
- The average patient age increased significantly in the later decade (2010-2020).
- A decrease in infections caused by compromised hosts and resistant bacteria (e.g., MRSA) was observed.
- A significant increase in infections due to indigenous oral and intestinal bacteria was noted in the later decade.
Conclusions:
- Recent infectious spondylitis cases show a rising trend of infections caused by indigenous oral and intestinal bacteria.
- This contrasts with a decrease in infections attributed to resistant bacteria over the past two decades.
- These evolving trends necessitate updated diagnostic and therapeutic approaches for spinal infections.
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