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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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Prevalence and Risk Factors of Cardiovascular Disease in Chronic Kidney Disease Patients at King Abdulaziz University
Rana A Nabalawi1, Mohammed Abdullah Bamuflih2, Abdullah Alaa Farid2
1Nephrology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
Cureus
|May 2, 2024
Summary
Cardiovascular disease (CVD) affects over half of chronic kidney disease (CKD) patients in Saudi Arabia. Key risk factors include diabetes, hypertension, and reduced heart function, highlighting the need for early intervention.
Area of Science:
- Nephrology
- Cardiology
- Public Health
Background:
- Chronic kidney disease (CKD) is a growing global health issue with increasing incidence.
- Cardiovascular diseases (CVD) represent a significant mortality risk for CKD patients.
- Limited research exists on CVD prevalence and risk factors in CKD patients within Saudi Arabia.
Purpose of the Study:
- To determine the prevalence of CVD among non-end-stage CKD patients at King Abdulaziz University Hospital (KAUH).
- To identify significant risk factors associated with CVD in this patient cohort.
- To provide data for targeted preventive strategies in Saudi Arabia.
Main Methods:
- Retrospective review of medical records for 465 non-end-stage CKD patients (aged 30-79) at KAUH from 2017-2022.
- Collection and statistical analysis of demographic, clinical, and laboratory data.
- Investigation of associations between patient characteristics and CVD diagnosis.
Main Results:
- Over half (56.3%) of CKD patients had a CVD diagnosis, primarily congestive heart failure and ischemic heart disease.
- Prevalent comorbidities included hypertension (84.7%) and diabetes mellitus (72.3%).
- Significant risk factors for CVD were severely reduced left ventricular ejection fraction, proteinuria, diabetes mellitus, and higher BMI.
Conclusions:
- This study provides crucial insights into CVD burden in CKD patients in Saudi Arabia.
- Identified risk factors underscore the importance of early CVD detection and intervention in CKD management.
- Findings can inform the development of targeted preventive strategies to reduce CVD risk in this population.
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