Related Experiment Video
Updated: Jun 27, 2025

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology
Published on: October 3, 2016
Instances of Biowarfare in World War I (1914-1918)
Ioannis Nikolakakis1,2, Spyros N Michaleas2, George Panayiotakopoulos3
1Emergency Department, Tzaneio Prefecture General Hospital of Piraeus, Athens, GRC.
Abstract:
During World War I (WWI), also referred to as 'The Great War,' Germany implemented a pioneering biowarfare program as part of a broader military strategy to undermine Allied forces by targeting their logistical and supply capabilities. This initiative, unprecedented in its systematic and strategic application, utilized a variety of pathogens, primarily targeting animal populations, to disrupt support systems without contravening international laws, specifically the 1907 Hague Convention. The operations, shrouded in secrecy and largely led by the German General Staff, included sophisticated sabotage actions against both enemy and neutral states. The allegations and usage of bioweapons increased the interest of the Great Powers in further developing their own biowarfare program.
Related Concept Videos
Defenses Against Pathogens and Herbivores
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Plant Breeding and Biotechnology
Bacterial Signaling
Transgenic Organisms
Biological Effects of Radiation

