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Published on: November 26, 2013
Thrombectomy using Zoom Reperfusion System in pediatric acute ischemic strokes: Case series and literature review
Raman Singh1, Uttam Verma1, Hakeem J Shakir2
1Department of Neurology, The Oklahoma University Health Sciences Center, USA.
Insights
The Zoom Reperfusion System shows promise for pediatric mechanical thrombectomies (MTs). Two pediatric cases demonstrated safe and effective clot removal in acute middle cerebral artery (MCA) syndrome, suggesting feasibility in younger patients.
Area of Science:
- Neuroendovascular surgery
- Pediatric neurology
- Vascular intervention
Background:
- Mechanical thrombectomies (MTs) are established for adult stroke but underrepresented in pediatrics.
- The Zoom Reperfusion System is a novel device for clot retrieval.
Purpose of the Study:
- To evaluate the safety and feasibility of the Zoom Reperfusion System in pediatric mechanical thrombectomies.
- To describe the outcomes of MT using the Zoom system in two pediatric cases.
Main Methods:
- Case report and literature review methodology.
- Utilized the Zoom Reperfusion System for clot retrieval in pediatric patients with acute middle cerebral artery (MCA) syndrome.
- Femoral access and advanced catheter techniques were employed.
Main Results:
- Successful recanalization achieved in both pediatric cases (TICI 2B and TICI 3).
- The Zoom system was safely navigated and engaged with the clot in both 14-year-old and 10-year-old patients.
- Case 1 involved right internal carotid artery (ICA) occlusion; Case 2 involved left ICA terminus occlusion.
Conclusions:
- The Zoom Reperfusion System appears feasible for pediatric mechanical thrombectomies.
- Further investigation with larger pediatric cohorts is necessary to confirm safety and efficacy.
Abstract:
IntroductionZoom reperfusion system (Imperative Care, CA) has proven to be promising for use in adult mechanical thrombectomies (MTs) but has not been described in pediatrics. We present two cases of a 14-year-old with acute right middle cerebral artery (MCA) syndrome and a 10-year old with acute left MCA syndrome who underwent MT using Zoom Reperfusion System safely with TICI 2B and TICI 3 recanalization, respectively.MethodCase report and literature review.ResultsA 14-year-old healthy boy with right supraclinoid internal carotid artery (ICA) occlusion (case 1) and a 10-year-old boy with left hypoplastic heart syndrome and left ICA terminus occlusion (case 2) were taken for MT after receiving alteplase at our institution. Through femoral access, an 8-French sheath was introduced into the right femoral artery through which a Zoom 88 catheter was introduced and parked at the right petrous ICA segment in case 1 and left ophthalmic ICA segment in case 2. Angiogram demonstrated complete ICA occlusion just past the ophthalmic artery origin in case 1 and at the ICA terminus in case 2. Zoom system (88 and 71) was then navigated to the face of clot with vacuum manifold engaged with the clot. TICI 2B (with the help of Trevo stent retriever [Stryker]) and TICI 3 recanalization were achieved in cases 1 and 2, respectively.ConclusionThe use of Zoom reperfusion system could potentially be feasible for use in pediatric age group. Larger pediatric patient population is needed to establish its safety.
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