Thrombectomy using Zoom Reperfusion System in pediatric acute ischemic strokes: Case series and literature review

Raman Singh1, Uttam Verma1, Hakeem J Shakir2

  • 1Department of Neurology, The Oklahoma University Health Sciences Center, USA.

PubMed

Insights

The Zoom Reperfusion System shows promise for pediatric mechanical thrombectomies (MTs). Two pediatric cases demonstrated safe and effective clot removal in acute middle cerebral artery (MCA) syndrome, suggesting feasibility in younger patients.

Area of Science:

  • Neuroendovascular surgery
  • Pediatric neurology
  • Vascular intervention

Background:

  • Mechanical thrombectomies (MTs) are established for adult stroke but underrepresented in pediatrics.
  • The Zoom Reperfusion System is a novel device for clot retrieval.

Purpose of the Study:

  • To evaluate the safety and feasibility of the Zoom Reperfusion System in pediatric mechanical thrombectomies.
  • To describe the outcomes of MT using the Zoom system in two pediatric cases.

Main Methods:

  • Case report and literature review methodology.
  • Utilized the Zoom Reperfusion System for clot retrieval in pediatric patients with acute middle cerebral artery (MCA) syndrome.
  • Femoral access and advanced catheter techniques were employed.

Main Results:

  • Successful recanalization achieved in both pediatric cases (TICI 2B and TICI 3).
  • The Zoom system was safely navigated and engaged with the clot in both 14-year-old and 10-year-old patients.
  • Case 1 involved right internal carotid artery (ICA) occlusion; Case 2 involved left ICA terminus occlusion.

Conclusions:

  • The Zoom Reperfusion System appears feasible for pediatric mechanical thrombectomies.
  • Further investigation with larger pediatric cohorts is necessary to confirm safety and efficacy.